The impact of maternal SARS-CoV-2 infection and its risk of vertical transmission is still not well known.

Recommendations from scientific societies seek to provide safety for newborns without compromising the benefits of early contact.

The aim of the study is to describe characteristics and evolution of newborns born to mothers with SARS-CoV-2 infection, as well as the implemented measures following recommendations from the Sociedad Española de Neonatología.

Observational, prospective and single-center cohort study.

A specific circuit was designed for mothers with SARS-CoV-2 infection and their newborns.

Epidemiological and clinical data were collected. PCR were performed in newborns at delivery and at 14 days of age.