The World Health Organization has recently declared a monkeypox outbreak as a public health emergency of global concern.

The main aim of this systematic review was to ascertain the maternal and perinatal outcomes of pregnancies complicated by monkeypox infection.

The Medline, Embase, and Cochrane databases were searched on June 25, 2022 utilizing combinations of the relevant medical subject heading terms, key words, and word variants for “monkeypox” and “pregnancy.”

The search and selection criteria were restricted to the English language.

The outcomes observed were miscarriage; intrauterine, neonatal, and perinatal death; preterm birth, vertical transmission, and maternal symptoms.

A metaanalysis of proportions was used to analyze the data.