בשל "הגנת זכויות יוצרים" מובא להלן קישור לתקציר המאמר. לקריאתו בטקסט מלא, אנא פנה/י לספרייה הרפואית הזמינה לך.

This study aimed to assess the rate of adverse obstetrical and neonatal outcomes in pregnancies diagnosed with confined placental mosaicism relative to that of unaffected controls.

Web-based databases were searched using relevant key words, and articles published from 1980 to February 2022 were retrieved.

Observational studies in English language including ≥10 cases of singleton pregnancies with diagnosis of confined placental mosaicism were included.

The diagnosis was established after detection of any chromosomal abnormality at chorionic villus sampling for any indication, followed by normal karyotype from amniotic fluid or neonatal leukocyte culture.

Two authors independently screened the references for eligibility, data extraction, and assessment of methodological quality using the Newcastle–Ottawa scale.

All available obstetrical and neonatal outcomes were recorded. Random-effect meta-analysis was performed to estimate pooled odds ratios and 95% confidence intervals of available outcomes in pregnancies with and without confined placental mosaicism.