We determined the anesthetic approach with the least adverse events and better cardiorespiratory stability profile, used in infants undergoing laser photocoagulation for retinopathy of prematurity.

A systematic review was conducted. PubMed, Scopus, and Cochrane Library were searched until 27th October 2021.

Reference lists of relevant studies, and abstract books of international annual meetings of pediatric Οphthalmology for the years 2020 and 2021 were also looked at, as well as Clinical trials registry (https://clinicaltrials.gov/).